Specimen: 5 mL (3 mL min.) Whole blood from 1 Green Top (Sodium Heparin) tube. Ship at 18-22°C. DO NOT FREEZE. Give brief clinical history.
Stability (Room): 48 hrs
Stability (Refrigerated): N/A
Stability (Frozen): N/A
Method: Stress Cytogenetics
Price: Contact Medialb
Turnaround time (TAT): 20 – 25 days
Usage: Chromosomes from a patient with a congenital form of bone marrow failure, Fanconi’s anemia (FA), are sensitive to clastogenic agents (chemicals causing DNA breakage) like Mitomycin C (MMC). The effect of MMC on lymphocytes in culture is used to differentiate reliably between FA patients with chromosome instability and Idiopathic aplastic anemia.
Home Collection: Available
Pre-test Information: Give brief clinical history.