Specimen: 50 mL (10 mL min.) aliquot of 24 hour urine. Collect urine with appropriate volume of 50% HCl to maintain pH between 1-2. Do not use concentrated HCl. Record 24 hour volume on test request form and urine container. Ship refrigerated or frozen. Patient should strictly avoid Theophylline, chocolate, vanilla, banana, alcoholic beverages, tea/coffee, tobacco and strenuous exercise at least 72 hrs before and during specimen collection.
Stability (Room): 8 hrs
Stability (Refrigerated): 7 days
Stability (Frozen): 30 days
Method: HPLC-EC
Comment: Initial testing for pheochromocytoma should always include measurement of plasma free metanephrines or urinary fractionated metanephrines or both. Recommended method to measure is LC-MS/MS OR HPLC-EC Also see PHEOCHROMOCYTOMA PROFILE.
Price: Contact Medilab
Turnaround time (TAT): 10 – 15 days
Usage: Elevated values of VMA along with other catecholamine metabolites are suggestive of catecholamine secreting tumor like Neuroblastoma, Pheochromocytoma and other Neural crest tumors. VMA levels may also be useful in monitoring patients who are also treated. Elevated levels are suggestive of Pheochromocytoma but not diagnostic.
Specialty: Oncologist
Disease: Cancer
Components:
Courier Charges:
Home Collection: Available
Department: HPLC
Pre-test Information: Patient should strictly avoid Theophylline, chocolate, vanilla, banana, alcoholic beverages, tea/coffee, tobacco and strenuous exercise at least 72 hrs before and during specimen collection.