Test CatalogueVw – Von Willebrand Antigen

Specimen: 3 mL whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 min. & finally transfer the supernatant (PPP) to 1 labelled clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

Stability (Room): 4 hrs

Stability (Refrigerated): 4 hrs

Stability (Frozen): 2 weeks

Method: Chemiluminescent Immunoassay (CLIA)

Comment: It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician.

Price: Contact Medilab

Turnaround time (TAT): 10 -15 days

Usage: von Willebrand factor is important for platelet-platelet & platelet-vessel hemostatic interactions. Decreased vWF antigen is seen in Congenital von Willebrand disease (vWD) and in acquired conditions associated with monocloncal gammopathies, lymphoproliferative disorders and autoimmune diseases. This assay is useful for the diagnosis of vWD and its subtyping. It also helps in differentiating vWD from Hemophilia A. The assay is also useful for monitoring therapeutic efficacy of treatment with vWF concentrates.

Specialty: Hematologist

Disease: Disorders of Coagulation

Components:

Courier Charges:

Home Collection: Available

Department:

Pre-test Information: Overnight fasting is preferred. It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

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